Abstract/Details

Evaluation of an intraoperative iodine-125 brachytherapy implant technique


2006 2006

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Abstract (summary)

The purpose of this study was to evaluate the usefulness of an intra-operative planning method in brachytherapy prostate seed placement by comparing pre-planning and intra-operative planning techniques. This comparison was achieved by a virtual-planning technique in which the pre-planned seed and needle positions are superimposed on the intra-operatively obtained volume study. Dosimetric evaluation of each implant was based on the dose volume histogram (DVH) generated from CT studies and analysis of image and seed numbers, target volume and inferior extent of posterior planes. These parameters showed that greater dosimetric values are noted in the intra-operative technique. The study demonstrated a benefit from an intra-operative approach to seed placement as opposed to a pre-planned approach. Defining the sagittal contours of the prostate, immediately prior to implant, reduced the inferior extent of seeds placed in the most posterior aspect of the prostate, thereby decreasing the probability for rectal complication and morbidity. Additionally, more correctly delineating the tranverse prostate contours at the time of seed placement resulted in fewer seeds placed in the periprostatic region, outside the PTV, thus reducing potential seed migration and increasing prostate dose coverage.

Indexing (details)


Subject
Biophysics;
Radiology;
Biomedical research
Classification
0760: Biophysics
0574: Radiology
0541: Biomedical research
Identifier / keyword
Health and environmental sciences; Applied sciences; Biological sciences
Title
Evaluation of an intraoperative iodine-125 brachytherapy implant technique
Author
Chaoui, Tserenpagma
Number of pages
29
Publication year
2006
Degree date
2006
School code
0506
Source
MAI 45/01M, Masters Abstracts International
Place of publication
Ann Arbor
Country of publication
United States
ISBN
9780542797668
Advisor
Patton, Phillip
University/institution
University of Nevada, Las Vegas
University location
United States -- Nevada
Degree
M.S.
Source type
Dissertations & Theses
Language
English
Document type
Dissertation/Thesis
Dissertation/thesis number
1436744
ProQuest document ID
304964615
Copyright
Database copyright ProQuest LLC; ProQuest does not claim copyright in the individual underlying works.
Document URL
http://search.proquest.com/docview/304964615
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