Ecotoxicology of metal-hydrocarbon mixtures in benthic invertebrates

2005 2005

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Abstract (summary)

Metal-hydrocarbon mixtures are becoming increasingly prevalent in natural environments due to expanding industrial activity and urbanization. The ecotoxicology of metal-hydrocarbon mixtures in benthic environments is of particular concern because both classes of contaminants partition to sediments and can thereby exert toxic effects in benthic organisms. Mixtures of dissimilar chemicals (including metals and hydrocarbons) are broadly hypothesized to elicit independent toxic effects however; this hypothesis has little supporting data. The purpose of this dissertation was to test this hypothesis for metal-hydrocarbon mixtures using environmentally relevant exposures and to determine mechanisms for observed interactive effects. Sediment and water-only bioassays were conducted employing the toxic heavy metal cadmium (Cd) and the polynuclear aromatic hydrocarbon phenanthrene (Phen) as model toxicants. Lethal and sublethal effects of singular and combined contaminants were examined in two freshwater species, the epibenthic amphipod Hyalella azteca and the bulk deposit-feeding benthic oligochaete Ilyodrihis templetoni. When interactive toxicity was observed, mixture effects on contaminant bioavailability, bioaccumulation and elimination were tested. As well, mixture effects on bioenergetics parameters were investigated and kinetic modeling was conducted to establish the source of mixture-mediated changes in contaminant bioaccumulation in I. templetoni . Cadmium-Phen mixtures caused independent effects in water-only exposures, but when incorporated into sediments, elicited synergistic lethal effects in H. azteca and antagonistic lethal effects in I. templetoni. Interactive effects were likely caused by Phen-mediated alterations in Cd bioaccumulation that resulted from changes in exposure via feeding.

The current basis for assessing ecotoxicological effects of contaminant mixtures in natural environments relies heavily on models derived from dosage-based mixture toxicology with considerably less emphasis on environmental science and biology. Understanding how contaminants interact toxicologically is important, but does not provide all the information necessary for assessing effects in natural populations that encounter contaminant mixtures in a diversity of natural environments. My experiments indicate that exposure source may be more important than dosage-based toxicological interactions in determining contaminant mixture effects in sediment environments. If this trend is widespread, understanding how species are exposed, determining the route of uptake and understanding how environmental characteristics affect exposure may be more important in determining mixture effects than mixture toxicology.

Indexing (details)

Environmental science;
Chemical engineering
0329: Ecology
0768: Environmental science
0542: Chemical engineering
Identifier / keyword
Health and environmental sciences; Applied sciences; Biological sciences; Benthic invertebrates; Ecotoxicology; Metals; PAHs
Ecotoxicology of metal-hydrocarbon mixtures in benthic invertebrates
Gust, Kurt A.
Number of pages
Publication year
Degree date
School code
DAI-B 66/03, Dissertation Abstracts International
Place of publication
Ann Arbor
Country of publication
United States
9780542025211, 0542025213
Fleeger, John W.
Louisiana State University and Agricultural & Mechanical College
University location
United States -- Louisiana
Source type
Dissertations & Theses
Document type
Dissertation/thesis number
ProQuest document ID
Database copyright ProQuest LLC; ProQuest does not claim copyright in the individual underlying works.
Document URL
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