Abstract/Details

Effects of dietary copper concentration and source on efficacy of phytase, phytate-phosphorus utilization, and intestinal microbiota in the chicken (<i>Gallus domesticus</i>)


2006 2006

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Abstract (summary)

High levels of dietary copper (Cu), up to 250 ppm, are normally added to poultry diets in the USA as a growth promoter and antimicrobial. However, reports of growth benefits of Cu on birds are not consistent and bactericidal/bacteriostatic effects and growth stimulation mechanisms are poorly understood. In addition, high levels of dietary Cu may affect the efficacy of phytase due to its high affinity for phytate. In the first study, effects of Cu concentration and source on in vitro phytate-P (PP) hydrolysis by phytase were investigated. Copper concentration, Cu source, and pH influenced PP hydrolysis by phytase in vitro and were related to the amount of soluble Cu and formation of insoluble Cu-phyate complex. Effects of dietary Cu addition at 250 ppm and source on digesta pH, and size of Ca, Zn and Cu complexes in intestinal digesta of broiler chickens were investigated in the second study. Copper supplementation and Cu source had no effects on pH of gizzard or duodenum+jejunum contents, however, Cu supplementation increased the pH of ileal contents (P < 0.05). Copper addition had no effects on Cu or Ca portions among soluble complexes of different molecular weight (MW) sizes but increased (P < 0.05) the percentage of Zn associated with large complexes (> 100,000 MW) by 46.08 to 59.56% and decreased (P < 0.05) the percentage of Zn associated with small complexes (< 5,000 MW) by 14.48 to 16.78%. Influence of dietary Cu concentration and source on intestinal microorganisms in vitro and in broiler chickens was studied in the third study. Lactobacilli showed quadratic increases to graded levels of Cu up to 125 ppm from Cu Sul, and E. coli showed quadratic decreases up to 250 ppm Cu from Cu Sul (P < 0.05). Addition of 187.5 ppm Cu from either Cu Sul or tri-basic Cu chloride (TBCC) had no effects on number of ileal Lactobacilli in broiler chickens. Supplementation with TBCC reduced coefficient similarity of the microbiota in ileal contents, whereas Cu Sul and TBCC had no effects on microbiota similarity coefficients or number of predominant species associated with the ileal mucosa.

Indexing (details)


Subject
Livestock;
Animal diseases
Classification
0475: Livestock
0476: Animal diseases
Identifier / keyword
Biological sciences; Chicken; Copper; Dietary; Gallus domesticus; Intestinal microbiota; Phosphorus; Phytase; Phytate-phosphorus
Title
Effects of dietary copper concentration and source on efficacy of phytase, phytate-phosphorus utilization, and intestinal microbiota in the chicken (<i>Gallus domesticus</i>)
Author
Pang, Yanfang
Number of pages
175
Publication year
2006
Degree date
2006
School code
0183
Source
DAI-B 68/05, Dissertation Abstracts International
Place of publication
Ann Arbor
Country of publication
United States
ISBN
9780549048008
Advisor
Applegate, Todd
University/institution
Purdue University
University location
United States -- Indiana
Degree
Ph.D.
Source type
Dissertations & Theses
Language
English
Document type
Dissertation/Thesis
Dissertation/thesis number
3263615
ProQuest document ID
305281250
Copyright
Database copyright ProQuest LLC; ProQuest does not claim copyright in the individual underlying works.
Document URL
http://search.proquest.com/docview/305281250/abstract
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