Abstract/Details

Concomitant Mycobacterium tuberculosis infection and type 2 diabetes: A descriptive model with global health implications


2010 2010

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Abstract (summary)

The type 2 diabetes (diabetes) pandemic is recognized as a threat to tuberculosis (TB) control worldwide. This secondary data analysis project estimated the contribution of diabetes to TB in a binational community on the Texas-Mexico border where both diseases occur. Newly-diagnosed TB patients > 20 years of age were prospectively enrolled at Texas-Mexico border clinics between January 2006 and November 2008. Upon enrollment, information regarding social, demographic, and medical risks for TB was collected at interview, including self-reported diabetes. In addition, self-reported diabetes was supported by blood-confirmation according to guidelines published by the American Diabetes Association (ADA). For this project, data was compared to existing statistics for TB incidence and diabetes prevalence from the corresponding general populations of each study site to estimate the relative and attributable risks of diabetes to TB. In concordance with historical sociodemographic data provided for TB patients with self-reported diabetes, our TB patients with diabetes also lacked the risk factors traditionally associated with TB (alcohol abuse, drug abuse, history of incarceration, and HIV infection); instead, the majority of our TB patients with diabetes were characterized by overweight/obesity, chronic hyperglycemia, and older median age. In addition, diabetes prevalence among our TB patients was significantly higher than in the corresponding general populations. Findings of this study will help accurately characterize TB patients with diabetes, thus aiding in the timely recognition and diagnosis of TB in a population not traditionally viewed as at-risk. We provide epidemiological and biological evidence that diabetes continues to be an increasingly important risk factor for TB.

Indexing (details)


Subject
Public health;
Epidemiology
Classification
0573: Public health
0766: Epidemiology
Identifier / keyword
Health and environmental sciences, Attributable risk, Comorbidity, Diabetes, Tuberculosis
Title
Concomitant Mycobacterium tuberculosis infection and type 2 diabetes: A descriptive model with global health implications
Author
Camerlin, Aulasa J.
Number of pages
75
Publication year
2010
Degree date
2010
School code
0219
Source
MAI 49/01M, Masters Abstracts International
Place of publication
Ann Arbor
Country of publication
United States
ISBN
9781124186818
Advisor
Restrepo, Blanca I.; Fisher-Hoch, Susan P.
Committee member
Fisher-Hoch, Susan P.; McCormick, Joseph B.; Restrepo, Blanca I.
University/institution
The University of Texas School of Public Health
Department
Epidemiology & Disease Control
University location
United States -- Texas
Degree
M.P.H.
Source type
Dissertations & Theses
Language
English
Document type
Dissertation/Thesis
Dissertation/thesis number
1480442
ProQuest document ID
751915678
Copyright
Database copyright ProQuest LLC; ProQuest does not claim copyright in the individual underlying works.
Document URL
http://search.proquest.com/docview/751915678
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