Abstract/Details

Risk factors of pneumonia in traumatic spinal-cord-injured patients


2011 2011

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Abstract (summary)

Pneumonia is a well-documented and common respiratory infection in patients with acute traumatic spinal cord injuries, and may recur during the course of acute care. Using data from the North American Clinical Trials Network (NACTN) for Spinal Cord Injury, the incidence, timing, and recurrence of pneumonia were analyzed. The two main objectives were (1) to investigate the time and potential risk factors for the first occurrence of pneumonia using the Cox Proportional Hazards model, and (2) to investigate pneumonia recurrence and its risk factors using a Counting Process model that is a generalization of the Cox Proportional Hazards model. The results from survival analysis suggested that surgery, intubation, American Spinal Injury Association (ASIA) grade, direct admission to a NACTN site and age (older than 65 or not) were significant risks for first event of pneumonia and multiple events of pneumonia. The significance of this research is that it has the potential to identify patients at the time of admission who are at high risk for the incidence and recurrence of pneumonia. Knowledge and the time of occurrence of pneumonias are important factors for the development of prevention strategies and may also provide some insights into the selection of emerging therapies that compromise the immune system.

Indexing (details)


Subject
Biostatistics;
Medicine
Classification
0308: Biostatistics
0564: Medicine
Identifier / keyword
Health and environmental sciences, Biological sciences, Counting process, Pneumonia, Recurrent events, Risk factors, Spinal cord injury, Survival analysis
Title
Risk factors of pneumonia in traumatic spinal-cord-injured patients
Author
Peng, Hui
Number of pages
47
Publication year
2011
Degree date
2011
School code
0219
Source
MAI 50/04M, Masters Abstracts International
Place of publication
Ann Arbor
Country of publication
United States
ISBN
9781267207432
Advisor
Frankowski, Ralph F.
Committee member
Burau, Keith D.; Ford, Charles E.; Xiong, Momiao
University/institution
The University of Texas School of Public Health
Department
Biostatistics
University location
United States -- Texas
Degree
M.S.
Source type
Dissertations & Theses
Language
English
Document type
Dissertation/Thesis
Dissertation/thesis number
1506945
ProQuest document ID
927934451
Copyright
Database copyright ProQuest LLC; ProQuest does not claim copyright in the individual underlying works.
Document URL
http://search.proquest.com/docview/927934451
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