Abstract/Details

Disorientation in Alzheimer disease: Allocentric and egocentric mechanisms


2012 2012

Other formats: Order a copy

Abstract (summary)

Introduction. Spatial disorientation is a common symptom of Alzheimer Disease (AD). The cognitive mechanisms of this difficulty have not been explored in this population. It is unclear which commonly used standard measures of neuropsychological function are more predictive of the risk of getting lost or disoriented. Ability to use allocentric and egocentric reference frames in AD has received little attention in research. We hypothesized that patients with AD will be more impaired on tasks of allocentric function than egocentric function and that this impairment will be more pronounced in AD sample compared to the healthy age-matched controls. Relative contributions of allocentric and egocentric functions to reports of orientation and wayfinding ability were explored. Method. Thirty-five participants (22 controls, 13 AD) were assessed with computer-based Allocentric-Egocentric Test, standardized measures of attention and executive function, and a self-report (controls) or caregiver-report (AD group) measure of daily wayfinding ability. Results. Participants with AD performed significantly worse than age-matched controls on all spatial tasks. Once the effects of interference that confounded performance on the Egocentric-I condition were controlled for (Egocentric-NI condition), participants with AD were more affected on the allocentric than the egocentric task. Participants with AD performed significantly worse on the allocentric task than age-matched controls, but performance on the egocentric task (Egocentric-NI) was not significantly different between the groups. Neuropsychological data revealed that attention and executive function together were highly predictive of all tests of spatial function regardless of frame of reference. However, only attention alone contributed significantly to the models on both egocentric tasks, and not on allocentric task. Executive function alone did not contribute significantly to any of the models. Performance on the allocentric and the two types of egocentric tasks together was highly predictive of reports of daily wayfinding ability, but none of these alone contributed significantly to the model. Conclusions . Allocentric functioning is differentially affected by the AD process compared to the egocentric functioning. Attention, but not executive function, is an important cognitive mechanism of egocentric, but not allocentric orientation. In our sample, ability to use either frame of reference alone did not explain daily wayfinding ability.

Indexing (details)


Subject
Behavioral psychology;
Cognitive psychology;
Alzheimers disease;
Neuropsychology
Classification
0384: Behavioral psychology
0633: Cognitive psychology
Identifier / keyword
Psychology; Allocentric functioning; Alzheimer's disease; Disorientation; Egocentric
Title
Disorientation in Alzheimer disease: Allocentric and egocentric mechanisms
Author
Nikelshpur, Olga M.
Number of pages
84
Publication year
2012
Degree date
2012
School code
0046
Source
DAI-B 73/07(E), Dissertation Abstracts International
Place of publication
Ann Arbor
Country of publication
United States
ISBN
9781267236296
Advisor
Foldi, Nancy S.
Committee member
Kluger, Alan; Li, Andrea; Majerovitz, Deborah; Stern, Yaakov
University/institution
City University of New York
Department
Psychology
University location
United States -- New York
Degree
Ph.D.
Source type
Dissertations & Theses
Language
English
Document type
Dissertation/Thesis
Dissertation/thesis number
3499310
ProQuest document ID
936471294
Copyright
Database copyright ProQuest LLC; ProQuest does not claim copyright in the individual underlying works.
Document URL
http://search.proquest.com/docview/936471294
Access the complete full text

You can get the full text of this document if it is part of your institution's ProQuest subscription.

Try one of the following:

  • Connect to ProQuest through your library network and search for the document from there.
  • Request the document from your library.
  • Go to the ProQuest login page and enter a ProQuest or My Research username / password.