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Bioresorbable Vascular Scaffolds in Routine PCI
In a randomized trial, 1845 patients undergoing PCI were assigned to receive either everolimus-eluting bioresorbable vascular scaffolds or everolimus-eluting metallic stents. The incidence of device thrombosis was higher with the bioresorbable scaffold than with the metallic stent.
see Original Article, N Engl J Med 2017;376:2319-2328
Treatment for Talaromyces marneffei
Talaromyces marneffei is a dimorphic fungus that causes substantial disease in Asia, especially among persons infected with the human immunodeficiency virus. In this randomized, controlled trial, initial therapy with amphotericin B was found to be superior to itraconazole.
see Original Article, N Engl J Med 2017;376:2329-2340
Buprenorphine in the Neonatal Abstinence Syndrome
In this single-center trial involving term infants with in utero opioid exposure, the use of sublingual buprenorphine resulted in a shorter duration of treatment and length of hospital stay than the use of oral morphine.
see Original Article, N Engl J Med 2017;376:2341-2348
Single-Nephron GFR in Healthy Adults
The glomerular filtration rate assesses the function of all nephrons, and the single-nephron GFR assesses individual nephron function. This study showed that in healthy adults, the single-nephron GFR remained constant regardless of age,...