Abstract/Details

Regional biomechanical properties of the articular surface, in the human distal femur, in health and disease

Trutiak, Nikolas.   University of Guelph (Canada) ProQuest Dissertations & Theses,  2011. MR80020.

Abstract (summary)

Osteoarthritis is the leading cause of disability among North American adults. This thesis investigates the design of a digital atlas capable of displaying elastic material properties and thickness mapped across the human distal femur. MicroCT scans and a double indentation stress-relaxation method were used to create the digital maps on steriolithographic images of femurs. Cartilage thickness, Poissons ratio and shear modulus were obtained from seven normal and six osteoarthritic knees. Significant sub-regional differences in the thickness and elastic properties of cartilage were identified over the trochlea, medial and lateral condyles. Consistent patterns are present in both healthy knees and osteoarthritic knees, although there were significant differences in the osteoarthritic group. Overall, a method was developed to non-destructively obtain thickness and elastic properties of the cartilage surface. Digital maps created using this technology can augment the capabilities of current image guided surgery systems during mosaic arthroplasty.

Indexing (details)


Subject
Biomedical engineering;
Biomechanics
Classification
0541: Biomedical engineering
0648: Biomechanics
Identifier / keyword
Applied sciences; Biological sciences
Title
Regional biomechanical properties of the articular surface, in the human distal femur, in health and disease
Author
Trutiak, Nikolas
Number of pages
142
Degree date
2011
School code
0081
Source
MAI 50/01M, Masters Abstracts International
ISBN
978-0-494-80020-1
Advisor
Hurtig, Mark B.; Gordon, Karen D.
University/institution
University of Guelph (Canada)
University location
Canada -- Ontario, CA
Degree
M.A.Sc.
Source type
Dissertation or Thesis
Language
English
Document type
Dissertation/Thesis
Dissertation/thesis number
MR80020
ProQuest document ID
889255534
Copyright
Database copyright ProQuest LLC; ProQuest does not claim copyright in the individual underlying works.
Document URL
https://www.proquest.com/docview/889255534