Abstract

Preexposure prophylaxis (PrEP) may prevent new human immunodeficiency virus (HIV) infections. At the project site, there was no consistent process in place for prophylaxis for HIV, so an evidence-based solution was sought. The purpose of this quantitative quasi-experimental quality improvement project was to determine if the implementation of the Centers for Disease Control and Prevention’s (CDC) Preexposure (PrEP) Practice Guideline would impact new PrEP prescriptions among high-risk adults in a community health center in urban California over four weeks. Nola Pender’s health promotion theory and Kurt Lewin’s change theory provided the theoretical underpinnings of the project. Data on PrEP prescriptions were extracted from the electronic health record. A total of N = 49 patients were included in the project, n = 22 in the comparison group, and n = 27 in the intervention group. A chi-square test showed no statistically significant difference in the PrEP prescription rate between the comparison group (36.4%, n = 8) and the implementation group (63.0%, n = 17), X2 (1, N = 49) = 3.43, p = .064. Despite the lack of statistical significance, clinical significance was demonstrated by a 26.6 % increase in PrEP prescriptions after the implementation. Based on these results, the CDC’s PrEP Practice Guideline may increase PrEP prescription rates. Recommendations are to continue using the CDC Preexposure (PrEP) Practice with PrEP guideline among high-risk adults at the project site, and to expand the project to other primary care clinics to obtain data on a larger sample size over an extended period.

Details

Title
Implementation of the CDC’s PrEP Practice Guideline to Improve PrEP Prescribing
Author
Usman, Dave M.
Publication year
2022
Publisher
ProQuest Dissertations & Theses
ISBN
9798352696453
Source type
Dissertation or Thesis
Language of publication
English
ProQuest document ID
2731430830
Copyright
Database copyright ProQuest LLC; ProQuest does not claim copyright in the individual underlying works.