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Abstract
Objective:
The aim of this study was to obtain data on susceptibility patterns of Escherichia coli strains responsible for community acquired urinary tract infections in a private hospital in Istanbul, Turkey.
Methods:
Between the dates of 1 January 2008 and 31 December 2008 patients admitted to the urology outpatient department with suspected urinary tract infection and urine samples of patients with reproductive culture results were evaluated retrospectively.
Results:
A total of 191 E. coli strains isolated from urine cultures which were processed between January 2008 and December 2008 in the clinical laboratory, were included in the study. Identification of bacteria and antibiotic susceptibility tests were performed by disk diffusion and automated system. Of E. coli strains, 14.6% (n=28) were found positive for ESBL. The resistance rates of E. coli strains were found as follows; 12.4% for nitrofurantoin, 40% for trimethoprim/sulfamethoxazole (TMP-SMX), 19.8% for ciprofloxacin and 19.2% for ceftriaxon.
Conclusion:
Empirical therapy should be based on local antimicrobial resistance monitoring in order to optimize the use of these drugs. (JAREM 2012; 2: 101-3)
Alternate abstract:
Amaç:
Bu çalışmada, İstanbul’da bir özel hastanede toplum kökenli üriner sistem enfeksiyonlarından izole edilen Escherichia coli suşlarında antimikrobiyal duyarlılıklarının belirlenmesi amaçlanmıştır.
Yöntemler:
Üroloji polikliniğine 1 Ocak 2008-31 Aralık 2008 tarihleri arasında ayaktan üriner sistem enfeksiyonu şüphesi ile başvuran ve idrar örneklerinde üreme saptanan hastaların kültür sonuçları retrospektif olarak değerlendirildi.
Bulgular:
İzole edilen 191 E. coli suşunda disk difüzyon ve/veya otomatize sistem testleri ile trimetoprim-sulfametoksazol (TMP-SMX) (%40), siprofloksasin (%19.8), seftriakson (%19.2) ve nitrofurantoin (%12.4), karşı direnç oranları saptandı. İzole edilen 191 E. coli’den 28’inde (%14.6) GSBL pozitif bulundu.
Sonuç:
Ampirik tedavi seçiminde, bölgesel antimikrobiyal direnç oranlarının bilinmesi, antibiyotiklerin etkin kullanılmasına katkıda bulunacaktır. (JAREM 2012; 2: 101-3)
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